中心简介
中心科室
教师队伍
科研成果
技术转移
联系我们
English
 
首页» 科研成果» 2015年»

科研成果

2015年
2014年
2013年
2012年

2015年>>

基因中心2015年发表的论文目录

1. Liu B(刘宝财,博士生,导师韩文玲), Su Y(苏玉,博士生,已毕业,导师韩文玲), Li T, Yuan W, Mo X, Li H, He Q, Ma D, Han W*(韩文玲). CMTM7 knockdown increases tumorigenicity of human non-small cell lung cancer cells and EGFR-AKT signaling by reducing Rab5 activation. Oncotarget. 2015 Oct 26. doi: 10.18632/oncotarget.5732. (article, IF 6.359)

2. Chong Wang(王宠,博士生,已毕业, 导师邱晓彦)Miaoran Xia, Xiaoping Sun, Zhiqiao He, Fanlei Hu, Lei Chen, Carlos E. Bueso-Ramos, Xiaoyan Qiu*(并列责任作者), C. Cameron Yin. IGK with conserved IGΚV/IGΚJ repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration. Oncotarget. 2015 In press(article, IF 6.359)

3. Qinyuan Liao(廖沁园,博士生,已毕业, 导师邱晓彦), Wei. Liu, Yang Liu, Fulin Wang, Chong Wang, Jingxuan Zhang, Ming Chu, Dongyang Jiang, Lin Xiao, Wenwei. Shao, Zhengzuo Sheng, Xia Tao, Lei Huo, C. Cameron Yin, Youhui Zhang, Gregory Lee, Jing Huang, Zihai Li, Xiaoyan Qiu*(邱晓彦). Aberrant High Expression of Immunoglobulin G in Epithelial Stem/Progenitor-like Cells Contributes to Tumor Initiation and Metastasis.Oncotarget.2015 Inpress(article, IF 6.359)

4. Pingzhang Wang*(王平章), Yehong Yang(杨晔宏), Wenling Han, Dalong Ma. ImmuSort, a database on gene plasticity and electronic sorting for immune cells. Sci Rep. 2015 May 19;5:10370. doi: 10.1038/srep10370.(article,IF 5.578)

5. Juan Xiao(肖娟,博士生,已毕业,导师陈英玉), Wenwei Liu, Yingyu Chen*(陈英玉),Wenbin Deng*. Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. J Neuroinflammation. 2015,12; 12(1):117. (2015,IF 5.408)

6. Min Xie, Ting Li(李婷),Ning Li, Jinlan Li, Qiumei Yao, Wenling Han, Guorui Ruan*(阮国瑞). VSTM-v1, a potential myeloiddifferentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients. J Hematol Oncol. 2015 Mar 15;8:25. doi: 10.1186/s13045-015-0118-4. (letter, IF: 4.812)

7. Ting Li(李婷), Yingying Cheng, Pingzhang Wang, Wenyan Wang, Fengzhan Hu, Xiaoning Mo, Hongxia Lv, Tao Xu*, Wenling Han*(韩文玲). CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma. J Exp Clin Cancer Res. 2015 Oct 16; 34(1):122. doi: 10.1186/s13046-015-0236-4. (article, IF 4.429)

8. Shiying Zhang(张石英,博士后,导师那彦群), Xiaolei Pei (co-FA裴晓磊,毕业博士生,导师王应), Hao Hu, Wenjuan Zhang, Xiaoning Mo, Kexin Xu*, Ying Wang*(王应, Yanqun Na. Functional characterization of the tumor-suppressor CMTM8 and its associated with prognosis in bladder cancer. Tumor Biology, 2015 Nov 28. [Epub ahead of print]. (article, IF 3.611)

9. Peng, S.(彭赛辉,博士生,导师赵红珊), Wang, K., Gu, Y., Chen, Y., Nan, X., Xing, J., Cui, Q., Chen, Y., Ge, Q.*(葛青), Zhao, H.*(赵红珊)TRAF3IP3, a novel autophagy up-regulated gene, is involved in marginal zone B lymphocyte development and survival. Clin. Exp. Immunol. 2015, 182(1):57-68 (article, IF 3.037)

10. Zhengzuo Sheng (盛正祚,联合培养博士生,导师徐涛),Yang Liu(刘洋,博士生,已毕业,导师邱晓彦), Caipeng Qin, Zhenhua Liu, Yeqing Yuan, FengZhan Hu, Yiqing Du, Huaqi Yin, Tao Xu, Xiaoyan Qiu*(邱晓彦). IgG is involved in the migration and invasion of clear cell renal cell carcinoma.J Clin Pathol. 2015;0:1–8. doi:10.1136/jclinpath-2015-202881 (IF:2.915).

11. Ming Tao, Xueying Shi, Chunhui Yuan, Jia Hu, Zhaolai Ma, Bin Jiang, Dianrong Xiu, Yingyu Chen*(陈英玉). Expression profile and potential roles of EVA1A in normal and neoplastic pancreatic tissues. Asian Pac J Cancer Prev. 2015; 16(1):373-6. (article, IF 2.514)

12. Dongyang Jiang(姜冬阳,博士生,已毕业,导师邱晓彦), Jing Ge, Qinyuan Liao, Junfan Ma, Yang Liu, Jing Huang, Chong Wang, Weiyan Xu, Jie Zheng, Wenwei Shao, Gregory Lee, Xiaoyan Qiu*(邱晓彦). IgG and IgA with Potential Microbial-binding Activity are Expressed by Normal Human Skin Epidermal Cells.Int. J. Mol. Sci. 2015, 16, 2574-2590.(article, IF 2.43)

13. Liu Y(刘洋,博士生,已毕业,导师邱晓彦), Liu D, Wang C, Liao Q, Huang J, Jiang D, Shao W, Yin CC, Zhang Y, Lee G, Qiu X*(邱晓彦). Binding of the monoclonal antibody RP215 to immunoglobulin G in metastatic lung adenocarcinomas is correlated with poor prognosis. Histopathology. 2015 Mar 9. (article, IF 2.33)

14. Jing Huang (黄晶), Lei Wang (DFCI博士后), Zhongyi Cong, Zohreh Amoozgar, Evgeny Kiner, Deyin Xing, Sandra Orsulic, Ursula Matulonis, Michael S. Goldberg*. The PARP1 inhibitor BMN 673 exhibits immunoregulatory effects in a Brca1-/- murine model of ovarian cancer. Biochem. Biophys. Res. Commun. 2015. 463(4):551-556. (article, IF 2.297. 在哈佛医学院做访问学者时完成)

15. Jingfang Liu, Miaoran Xia, Pingzhang Wang, Chong Wang, C. Cameron Yin, Xiaoyan Qiu*(邱晓彦). Immunoglobulin gene expression in umbilical cord blood-derived CD34+ hematopoietic stem/progenitor cells. Gene. 2015 In press(article, IF 2.13)

16. Wenjuan Zhang (张文娟,毕业博士生,导师马大龙), Hui Qi (綦辉,毕业博士生,导师马大龙), Xiaoning Mo, Qianying Sun, Ting Li, Quansheng Song, Kexin Xu, Hao Hu, Dalong Ma, Ying Wang*(王应). CMTM8 is frequently downregulated in multiple solid tumors. Appl Immunohistochem Mol Morphol, 2015 Nov 16. [Epub ahead of print]. (article, IF 2.012)

17.     Fu W(付伟伟,博士生,已毕业,导师:韩文玲), Cheng Y, Zhang Y, Mo X, Li T, Liu Y, Wang P, Pan W, Chen Y, Xue Y, Ma D, Zhang Y, Han W*(韩文玲). The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells. J Interferon Cytokine Res. 2015 Sep;35(9):720-33. (article, IF 2.000)

18. Liu H(刘绘绘,博士生,已毕业,导师:韩文玲), Zou X, Li T, Wang X, Yuan W, Chen Y, Han W*(韩文玲). Enhanced production of secretory glycoprotein VSTM1-v2 with mouse IgGκ signal peptide in optimized HEK293F transient transfection. J Biosci Bioeng. 2015 Jun 30. pii: S1389-1723(15)00209-1.4  (article, IF 1.884)

19. Liu H(刘绘绘,博士生,已毕业,导师:韩文玲), Wang X, Shi S, Chen Y, Han W*(韩文玲). Efficient production of FAM19A4, a novel potential cytokine, in a stable optimized CHO-S cell system. Protein Expr Purif. 2015 Sep;113:1-7. doi: 10.1016/j.pep.2015.05.004. Epub 2015 May 12. (article, IF 1.695)

20. Liang P, Wang X, Wang R, Wan Z, Han W*韩文玲), Li R*. CARD9 deficiencies linked to impaired neutrophil functions against Phialophora verrucosa. Mycopathologia. 2015 Jun;179(5-6):347-57article, IF 1.528

21. 邱晓彦*. 非B细胞来源的免疫球蛋白促进肿瘤的发生和发展(专家论坛). 中国肿瘤生物治疗杂志. 2015;22(2):183-190.

22. Pingzhang Wang, Huiying Qu, Shibin Song, Shuang Li, Ningyu Huang, Wenling Han, Dalong Ma. ImmuCo: a database of gene co-expression in immune cells. Nucleic Acids Res. 2015 Jan;43(Database issue):D1133-9. doi: 10.1093/nar/gku980. Epub 2014 Oct 17.(article,IF: 9.112)(今年出版)

23. Juan Xiao, Ge Li, Jia Hu, Liujing Qu, Dalong Ma, Yingyu Chen. Anti-inflammatory effects of recombinant human PDCD5 (rhPDCD5) in a rat collagen-induced model of arthritis. Inflammation. 2015, 38(1):70-78 (article, IF 2.5)(今年出版)

24.  Ting Li, Xiaohuan Guo, Wenyan Wang, Xiaoning Mo, Pingzhang Wang, Wenling Han. V set and transmembrane domain containing 1 is silenced in human hematopoietic malignancy cell lines with promoter methylation and has inhibitory effects on cell growth. Mol Med Rep. 2015 Feb;11(2):1344-51. (article, IF: 1.554)  (今年出版)

 

 

2015年申请及授权专利

专利号

申请日

专利名称

发明人

专利权人

专利类型

授权日

ZL201010188344.1

发明专利

授权日:2015826

人类基因FAM96A及其蛋白质的应用

负责人:王露

其他发明人:金鹏,王兰兰,马大龙,张颖妹,宋泉声

北京大学

201510776270.6发明专利

申请日:20151113

人类细胞因子CCDC134在自身免疫性疾病中的应用

负责人:黄晶

其他发明人:夏鹏,余骉亿,巩晓婷,肖琳,邱晓彦

北京大学

201510781258.4

发明专利

申请日:20151113

PSMP的单克隆抗体及其用途

负责人:王应

其他发明人:马大龙,郑丹凤,裴晓磊,佘少平,彭新建,陈迪新,郑璨,梁炜薇,宋泉声,张颖妹

北京大学

201510776518.9

发明专利

申请日:

20151115

non B-sIgG作为上皮性干/祖细胞标志物的应用

负责人:邱晓彦

其他发明人:廖沁园,刘伟,刘洋,黄晶

北京大学

 

版权所有:北京大学人类疾病基因研究中心      地址:北京市海淀区学院路38号 邮编:100191    电话: 010-82802846