| 名称 |
曾用名 |
配体 |
生物功能 |
| C Receptor Subfamily |
| XCR1 |
GPR5 |
XCL1 & 2 (Lymphotactin) |
炎症 |
| CC Receptor Subfamily |
| CCR1 |
CKR1 |
CCL14 (HCC-1) |
抗病毒应答 |
| CCR2 |
CKR2 |
CCL2 (MCP-1) |
巨噬细胞募集 |
| CCR3 |
CKR3 |
CCL11 (eotaxin) CCL24 (eotaxin-2) |
寄生虫应答, Th2募集 |
| CCR4 |
CKR4 |
CCL17 (TARC), CCL22 (MDC, ABCD-1, DC/B-CK) |
向皮肤归巢，Th2募集 |
| CCR5 |
CKR5 |
CCL4 (MIP-1) beta |
Th2细胞和巨噬细胞募集 |
| CCR6 |
STRL22 |
CCL20 (exodus-1, MIP-3a, LARC, ST38) |
树突状细胞归巢 |
| CCR7 |
EBI1 |
CCL19 (exodus-3, ELC, MIP-3 beta, CK beta11),
CCL21 (exodus-2, SLC, 6-Ckine, TCA4, CK beta9) |
T细胞, B细胞和树突状细胞向次级淋巴组织归巢；自然杀伤细胞募集 |
| CCR8 |
TER1 |
CCL1 (I-309, TCA3) |
Th2 募集 |
| CCR9 |
GPR9-6 |
CCL25 (TECK, Ck beta15) |
向肠道归巢, 胸腺细胞迁移 |
| CCR10 |
GPR2 |
CCL27 (ALP, 皮肤kine, ILC, E皮肤e, CTAK), CCL28 |
T细胞向皮肤归巢 |
| CCR11 |
PPR1 |
CCL2 (MCP-1) CCL19 (exodus-3, ELC, MIP-3 beta,
CK beta11) |
巨噬细胞募集 |
| DARC |
|
Many CC |
疟原虫受体 |
| CXC Receptor Subfamily |
| CXCR1 |
IL-8RA |
|
嗜中性细胞趋化和失调 |
| CXCR2 |
IL-8RB |
CXCL1 (GRO alpha, MGSA, N51/KC [mouse], MIP-2) |
|
| |
|
CXCL7 (PBP, CTAPIII, beta-TG, NAP-2) CXCL5 (ENA-78) |
嗜中性细胞趋化和失调 |
| CXCR3 |
GPR9 |
CXCL10 (gamma IP-10, crg-2 [mouse]) |
|
| |
|
CXCL11 (H174, beta-R1, I-TAC, IP-9) CXCL9 (mig) |
T细胞应答 |
| CXCR4 |
LESTR |
CXCL12 (SDF-1 alpha, SDF-1 beta, PBSF) |
B细胞应答, 干细胞归巢 |
| CXCR5 |
BLR1 |
CXCL13 (BLC, BCA-1) |
B细胞应答 |
| CXCR6 |
Bonzo |
CXCL16 |
活化的 T细胞 |
| CX3C Receptor Subfamily |
| CX3CR1 |
V28 |
CX3CL1 (Fractalkine, neurotactin [mouse]) |
炎症 |
| 参考文献：Christopherson K 2nd,
Hromas R. Stem Cells 2001;19(5):388-96 Chemokine regulation
of normal and pathologic immune responses. |
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