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Research projects supported by The Peking University Center For Human Disease Genomics |
| 编号 |
项目名称
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| A-1 | 人肝细胞色素P（CYP450）基因多态性与药物氧化代谢相关性的研究 The relationship between hepatocytes cytochrome P450 genetic polymorphism and drugs metabolism in Chinese population |
| A-2 | 两种新基因结构的研究 Structural and functional analyses of two novel genes |
| A-3 | 人类肿瘤转移相关基因的克隆和功能研究 Cloning and functional studies of human cancer metastasis-related gene |
| A-4 | 同型半胱氨酸诱导基因在人胚心脏发育中的表达及作用 The expression and effect of homocysteine derived gene on heart development of human embryo |
| A-5 | 端粒酶hTRT基因转录调节因子克隆及其功能研究 Cloning and functional studies of transcriptional factors of telomerase hTRT gene |
| A-6 | 肿瘤及胚胎组织特异表达基因P65的功能研究 Function of a novel gene P65 specially expressed in cancer and embryotic tissues |
| A-7 | （1） 人肝癌相关新基因（hctp）的结构与功能的研究（2）Liprinβ1基因家族中一个新的剪接本的生物学作用的研究 (1)Structure and function of a novel gene associated with hepatocellular carcinoma (2)Biological role of a novel splicing form of liprin β1 gene family |
| A-8 | 应用单核苷酸多态性研究典型儿童失神癫痫的基因 Utilizing single nucleotide polymorphism to study the genes of typical childhood absence epilepsy |
| A-9 | 家族性热性惊厥致病基因遴选与应用Sorting out and applying of febrile conmulsions gene |
| A-10 | Cx26基因多态性及与中国人遗传性耳聋的关系 SNP of connexin 26 gene and the relation between SNP and genetic deafness in Chinese population |
| A-11 | 慢性家族性良性天疱疮基因突变及发病机制研究 Chronic family benign pemphigus gene mutation and molecular biologic pathogenesis |
| A-12 | 白血病和淋巴瘤相关基因的SNP研究 Research of SNPs in leukemia and lymphoma relative genes |
| A-13 | 激素抵抗型肾病综合征与糖皮质激素受体基因多态性的关系 Correlation between steroid resistant nephritic syndrome and the polymorphism of glucocorticosteroid receptors |
| A-14 | 神经蜡样质肢褐素沉积病不同亚型的基因研究 Gene analysis in different form of neuronal ceroid lipofuscinosis |
| A-15 | 线粒体肌病和脑肌病患者线粒体DNA单核苷酸多态性的研究 Study of single nucleotide polymorphisms of mitochondrial DNA in patients with mitochondrial myopathy and encephalomyopathy |
| A-16 | 妊娠高血压家系相关基因研究 Study on the gene contributing to pregnancy induced hypertension |
| A-17 | Collectrin在人类肾脏疾病慢性进展过程中的作用 Function analysis of Collectrin, a novel collecting tubule-specific gene, in the progressive process of renal diseases |
| A-18 | 肾癌发生发展相关基因克隆及其功能应用研究 Cloning and functional research of renal cell carcinoma related genes |
| A-19 | 雌、孕激素受体基因改变与子宫内膜癌的关系 Genetic changes of estrogen receptor and progesterone receptor in endometrial carcinoma |
| A-20 | 动脉硬化单核苷酸多态性分析 Analysis of single nucleotide polymorphisms in patients with atherosclerosis |
| A-21 | 系膜增生性肾小秋肾炎及慢性化进展相关基因克隆和鉴定 Cloning and identification genes related to the progression of mesangial proliferative glomerular nephritis |
| A-22 | 高血压患者药物敏感基因的筛选及功能测定研究 Selection and function determination of drug-sensitive genes in patients with essential hypertension |
| A-23 | 线粒体基因缺失比例与噪声性耳聋个体易感性关系的研究 Relationship between proportion of mitochondrial DNA with gene deletion and individual susceptive to noise-induced hearing loss |
| A-24 | 子宫颈癌基因表达模式的系统研究（SAGE） Serial analysis of gene expression（SAGE） in cervical cancer |
| A-25 | 慢性阻塞性肺部疾病相关基因的研究 `Genetic susceptibility to chronic obstructive pulmonary disease in study of MMP(1,9),GSTM1, alpha-AT and IL-8(CXCR1,CXCR2) |
| A-26 | 特发性男性不孕不孕患者Y染色体微缺失筛查分析 Study on Y chromosome microdeletion in idiopathic infertility |
| A-27 | 孤立性房颤相关致病基因的研究 The studies of the association between the candidate genes and the lone arterial fibrillation |
| A-28 | 细胞粘附相关分子调控肿瘤转移的机理及应用研究 The mechanism of cell adhesion related molecules in the regulation of carcinoma cell metastasis and their implied appliance |
| A-29 | 胃癌易感相关基因的表达和结构多态性研究 Polymorphic status of expression and structure of genes related to susceptibility of gastric carcinoma |
| A-30 | 胃癌、食道癌高危人群易感基因筛选 Screening of susceptible genes for high risk population of gastric and esophageal cancers |
| A-31 | 吗啡依赖Wistar大鼠与正常大鼠脑mRNA的差异显示及基因芯片分析 Gene expression study on the normal and morphine-dependent Wistar rats with DD-PCR and gene chips |
| A-32 | 国人Alzheimer病、精神分裂症和儿童孤独症单核苷酸多态性研究 Study on SNPs for Alzheimer's disease, schizophrenia and autism in Chinese population |
| A-33 | 癌细胞内Ig样蛋白的基因序列及生物学活性探讨 Gene cloning and functional study of Ig-like proteins in cancer cells |
| A-34 | 标准化乳腺癌冷冻样本的收集 Collection of frozen breast cancer tissues |
| A-35 | 标准化胃癌组织和细胞库的建立 Rebuild of the standard tissue and cell banks for gastric cancer |
| A-36 | 标准化组织标本库的建立 Establishing of standardized tissue bank |
| A-37 | 标准化组织标本数据库的建立 Establishing of standardized tissue bank database |